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Products > Peptide human growth hormone > > Bremelanotide/ PT-141 10mg/vial
Bremelanotide/  PT-141 10mg/vial
Bremelanotide/  PT-141 10mg/vial
Product name : Bremelanotide/ PT-141 10mg/vial
Item : 189691-06-3
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Quick details:

 

PT-141 Bremelanotide

Molecular Formula: C50H68N14O10

Molecular Weight: 1025.16

CAS NO:189691-06-3

Standard:USP 99%

Structural Names: cyclo-[Nle4, Asp5, D-Phe7, Lys10]alpha-MSH-(4-10) 

Appearance White powder White powder

Solubility Soluble in water and 1% acetic acid Conforms

Specifical Optical Rotation -50°~-60°(c=1,1%HAc) -55.65°

Peptide Purity (By HPLC) ≥ 98.0% by area integration 99.67%

 

Description:


 

PT-141(Bremelanotide)is the first of a new class of drugs called melanocortin agonists being developed to treat sexual dysfunction. The mechanism of action of PT-141 (Bremelanotide)may offer significant safety and efficacy benefits over currently available products because it acts on the pathway that controls sexual function without acting directly on the vascular system.

 

PT-141 or Bremelanotide is the generic term for a research peptide being studied for its possible use in helping to improve sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder). PT-141 was developed from the tanning peptide Melanotan 2, which is a synthetically produced variant of a peptide hormone naturally produced in the body that stimulates melanogenesis that is known as alpha-Melanocyte stimulating hormone. MSH, activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido.

 

PT-141 for Sexual Dysfunction:

 

PT-141 is a potential remedy for the treatment of sexual dysfunction; specifically, male erectile dysfunction. Studies have shown that PT-141 does not act on the vascular system like former compounds, but allegedly works by activating melanocortin receptors in the brain, therefore helping increase ones sexual stimulation. PT-141 is a melanocortin based peptide that has shown effectiveness in clinical studies on both male and female rats. Male rats have shown erectile response with doses as low as 1-2 mgs whereas most female rats have shown positive results with higher doses around 2-3 mgs. While the dosage requirements tend to be higher for female rats, the observable results in female rats tend to be stronger.

 

PT-141 Specification:

 

Appearance White powder

Single Impurity (HPLC) 1.0%max

Amino Acid Composition ±10% of theoretical

Peptide Content (N%) ≥80.0% 

Water Content(Karl Fischer) ≤6.0%

Acetate Content (HPIC) ≤15.0%

MS(ESI)Consistent

Mass Balance 95.0~105.0%

 

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Peptide list:

 

MGF

2mg/vial

PEG MGF  

2mg/vial

CJC-1295 with DAC

2mg/vial

CJC-1295 without DAC   

2mg/vial

PT-141  

10mg//vial

MT-1   

10mg//vial

MT-2  

10mg//vial

GHRP-2    

5mg//vial

GHRP-2  

10mg//vial

GHRP-6  

5mg//vial

GHRP-6 

10mg//vial

Ipamorelin  

2mg//vial

Hexarelin 

2mg//vial

Sermorelin    

2mg//vial

Oxytocin 

1g, 2mg//vial

TB500   

2mg//vial

pentadecapeptide BPC 157 

2mg//vial

HGH 176-191   

2mg//vial

Triptorelin   

2mg//vial

Tesamorelin    

2mg//vial

Gonadorelin     

2mg//vial

Gonadorelin     

10mg//vial

DSIP  

2mg//vial

Selank  

5mg//vial  



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